Evaporative Light Scattering Detectors (GPC)

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Varian 380-LC & 385-LC

It is well recognized that evaporative light scattering detectors (ELSD) can outperform traditional detectors when analysing non-chromophoric samples by HPLC, as the detection method does not rely on the optical properties of the analyte. ELSD detectors detect all compounds less volatile than the mobile phase, and with the advantage of low temperature operation, the benefits of ELSD compared to UV or RI now apply to an even wider range of HPLC applications.

Polymer Laboratories (PL), now a part of Varian, Inc., is a world leader in the design, build, service, and support of evaporative light scattering detectors, with almost 20 years' experience in this field. PL's ELSDs continue to lead the way in the development of the technology, with the performance of our instruments matched to customers' requirements.

PL Varian's three models of ELSD will deliver you high quality, high sensitivity, state of the art evaporative light scattering detection at an affordable price.

Applications Areas

  • Pharmaceuticals
  • Nutraceuticals
  • Combinatorial libraries
  • Carbohydrates
  • Lipids
  • Phospholipids
  • Triglycerides
  • Fatty acids
  • Amino acids
  • Polymers
  • Surfactants

For further information on ELSD applications visit our Technical Bulletin Download section.

Analysis

Varian 380-LC

Varian 385-LC

HPLC analysis of non-volatile compounds

Y

Y
HPLC analysis of semi-volatile compounds

Y

Y
Highly volatile compounds

Y

X
Ambient GPC Analysis

Y

Y
High temperature GPC analysis X X

Specifications

Analysis

Varian 380-LC

Varian 385-LC

Light Source LED 480 nm LED 480 nm
Detector Photomultiplier tube digital signal processing Photomultiplier tube digital signal processing
Temperature Range
Evaporator
Nebulizer
Heated Transfer Line (opt)

OFF, 30 - 120 ºC
OFF, 30 - 90°C
Not available

OFF, 10 - 80 ºC
OFF, 25 - 90°C
Not available
Nebulizer
Typical Inlet Pressure
Maximum Inlet Pressure
Gas Flow Rate

60 - 100psi
100psi
0.9 - 3.25 SLM

60 - 100psi
100psi
0.9 - 3.25 SLM
Eluent Flow Rate 0.2 - 5 mL/min 0.2 - 5 mL/min
Analog Output 0 - 1V FSD 0 - 1V FSD

Digital Output

24 bit digital data, 10 or 40 Hz 24 bit digital data, 10 or 40 Hz
Communications

Serial (RS232),
Remote start Input,
Remote A/Z
Contact Closure
TTL

Serial (RS232),
Remote start Input,
Remote A/Z
Contact Closure
TTL

Operation

Graphical Vacuum fluorescent
display with keypad Real-time control via ELSD Dimension Software
Ten predefined methods

Graphical Vacuum fluorescent
display with keypad Real-time control via ELSD Dimension Software
Ten predefined methods

Power Requirements 90/120V AC or 220/250V AC,
50/60Hz 2A max
90/120V AC or 220/250V AC,
50/60Hz 2A max
Dimensions (wxdxh) 200x450x415 mm 200x450x415 mm
Weight 13 kg 13 kg