PL-Latex

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Uniform latex particles are used in a wide range of applications which exploit their physico-chemical properties in sophisticated immunoassay formats, both in medicine and veterinary science.  To meet this need, Polymer Laboratories (PL), now a part of Varian, Inc., manufactures latexes with both essentially uncharged surfaces for immobilization of biomolecules by adsorption, and surfaces having carboxyl or aldehyde groups, allowing covalent immobilization of ligands.  PL's intensely-colored HiDyeTM particles are ideal for membrane migration assays and cell labelling studies.

PL-Latex particles have been employed for many years in a variety of assay formats for rapid, user-friendly and cost-effective diagnostic tests.

Applications in Immunodiagnostic Assay Systems

  • Slide Agglutination
  • Membrane Migration
  • Particle Capture
  • Turbidimetry
  • Nephelometry
  • 'Particle Enhanced' Assays

HiDyeTM Intensely-Colored Particles

PL's intensely-colored HiDyeTM particles offer all the features of the white particles with the added advantage of intense color.  As the dye is not surface bound, it does not interfere with the binding of the ligand. 

PL's innovative research into highly-dyed colored particles played a primary role in assisting diagnostic companies in the development of the first membrane capture and migration assays, in the adoption of a color-coded identification system for diagnostic test reagents and cell labelling studies.

Custom Synthesis Service

In addition to our commercial latexes, PL offers a completely confidential custom synthesis service tailored to your exact needs.  Whether for small volume applications or research and development scale, PL can manufacture small scale batches cost-effectively, reducing your development costs and ensuring a rapid turnaround time. If you require latex particles of a defined size, color, surface functionality or with fluorescent characteristics, contact us to discuss your requirements.

Contract Manufacturing with Confidence

PL also undertakes contract manufacturing for some of the world's largest diagnostic and pharmaceutical companies, utilizing their proprietary technology under license together with PL's particle expertize.