Varian 385-LC ELSD

Evaporative light scattering detectors are ideal for detecting analytes with no UV chromophore as they do not rely on the optical properties of a compound. The Varian 385-LC Evaporative Light Scattering Detector is the latest high performance ELS detector from Varian Polymer Laboratories, with almost 20 years’ experience in the design and manufacture of evaporative light scattering detectors.

The Varian 385-LC Evaporative Light Scattering Detector is the only ELSD that delivers sub-ambient operation, for unrivalled detection of thermally labile analytes. Designed for the analysis of all compounds, the Varian385-LC delivers evaporation down to 10 °C, providing maximum sensitivity for compounds with significant volatility below 30 °C. Programmable control of gas flow and temperature during an injection eliminates solvent gradient effects and maximizes response for improved accuracy. To detect everything you inject with high sensitivity, the Varian 385-LC is the ELSD of choice for all applications.

Key Benefits

• High sensitivity provides superb responses for all compounds, down to low nanogram levels.
• Sub-ambient operation using a Peltier cooled evaporation tube delivers temperatures down to
  10 °C, preventing degradation of the thermally labile compounds that other ELSDs cannot detect.
• Real-time control during an injection via programmable Dimension Software maintains maximum sensitivity throughout the run.
• Real-time gas programming eliminates solvent enhancement effects during gradient elution, for excellent quantification.
• Low dispersion and high-speed data output rates are the perfect match for Fast LC applications.
• Superb reproducibility below 2 % gives reliable and accurate results.
• Multi-vendor software control and data acquisition using Varian’s Galaxie™ chromatography data system, and other vendors’ interfaces, eliminates the need for an analog to digital converter.
• Rapid heating and cooling of the evaporator tube minimizes equilibration time and increases sample throughput.
• Full DMSO transparency ensures that responses from early eluting compounds are not hidden.
• Fully integrated with the Varian 920-LC analytical HPLC system for the complete chromatographic solution.
• Complementary to LC/MS.

Advantage Notes

Real-time Gas Control Overcomes Solvent Gradient Effects (PDF, 118KB)

Overcoming Compound Volatility with Sub-ambient ELSD (PDF, 84KB)

For administrative reasons, part numbers are now prefixed with PL, however, there is no change to technical specification. Please update your records and use this revised part number format when ordering in future.